Congenital Melanocytic Nevus Syndrome: A Case Series
نویسندگان
چکیده
منابع مشابه
Congenital Melanocytic Nevus Syndrome: A Case Series.
Congenital melanocytic nevus syndrome (CMNS) is the result of an abnormal proliferation of melanocytes in the skin and central nervous system caused by progenitor-cell mutations during embryonic development. Mutations in the NRAS gene have been detected in many of these cells. We present 5 cases of giant congenital melanocytic nevus, 3 of them associated with CMNS; NRAS gene mutation was studie...
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Agminated nevus is a cluster group of melanocytic nevi confined to a localized area of the body. There are many pigmented lesions described in the literature as agminated, such as blue nevi, multiple lentigines and Spitz nevi, but only a few cases of congenital agminated melanocytic nevi have been described. We report a case of a male child who presented with congenital agminated nevi, emphasiz...
متن کاملBlaschkolinear congenital melanocytic nevus.
common acquired nevi and an otherwise normal clinical examination. Congenital melanocytic nevi are often classified according to their size [1] . Another attempt of classification in two groups has recently been proposed: type I, the most frequent, with a single lesion involving one anatomic area and type II, less common, with a larger lesion and dozens of smaller ones, with a similar pattern o...
متن کاملGiant congenital melanocytic nevus*
Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major ps...
متن کامل[Proliferative nodule in a congenital melanocytic nevus].
There are several benign lesions that may appear on conventional melanocytic nevi and clinically or histologically simulate malignant transformation while they actually behave in a benign manner.1 These include proliferative nodules, which show a particular tendency to develop on giant congenital melanocytic nevi (although they are also seen on smaller lesions) and, to a lesser degree, on acqui...
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ژورنال
عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)
سال: 2017
ISSN: 1578-2190
DOI: 10.1016/j.adengl.2017.08.018